Bone marrow transplantation prolongs life span and ameliorates neurologic manifestations in Sandhoff disease mice.

The GM2 gangliosidoses are a group of severe, neurodegenerative conditions that include Tay-Sachs disease, Sandhoff disease, and the GM2 activator deficiency. Bone marrow transplantation (BMT) was examined as a potential treatment for these disorders using a Sandhoff disease mouse model. BMT extende...

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Detaylı Bibliyografya
Asıl Yazarlar: Norflus, F, Tifft, C J, McDonald, M P, Goldstein, G, Crawley, J N, Hoffmann, A, Sandhoff, K, Suzuki, K, Proia, R L
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1998
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC508774/
https://ncbi.nlm.nih.gov/pubmed/9576752
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