Expression of the human histocompatibility leukocyte antigen DR3 transgene reduces the severity of demyelination in a murine model of multiple sclerosis.

The role of various MHC genes in determining the progression of multiple sclerosis (MS) remains controversial. The HLA-DR3 gene has been associated with benign relapsing MS in some genetic epidemiologic studies, but with disease progression in others. We induced demyelination in highly susceptible B...

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Autors principals: Drescher, K M, Nguyen, L T, Taneja, V, Coenen, M J, Leibowitz, J L, Strauss, G, Hammerling, G J, David, C S, Rodriguez, M
Format: Artigo
Idioma:Inglês
Publicat: 1998
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC508759/
https://ncbi.nlm.nih.gov/pubmed/9541508
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