Macrophage-derived nitric oxide initiates T-cell diapedesis and tumor rejection

In tumor biology, nitric oxide (NO) is generally regarded as an immunosuppressive molecule that impedes T-cell functions and activation of endothelial cells. Contrasting with this view, we here describe a critical role for NO derived from inducible nitric oxide (iNOS)-expressing tumor macrophages in...

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Pubblicato in:Oncoimmunology
Autori principali: Sektioglu, Ibrahim M., Carretero, Rafael, Bender, Noemi, Bogdan, Christian, Garbi, Natalio, Umansky, Viktor, Umansky, Ludmila, Urban, Katharina, von Knebel-Döberitz, Magnus, Somasundaram, Veena, Wink, David, Beckhove, Philipp, Hämmerling, Günter J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2016
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087300/
https://ncbi.nlm.nih.gov/pubmed/27853636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1204506
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