Downregulation of miR-199b is associated with distant metastasis in colorectal cancer via activation of SIRT1 and inhibition of CREB/KISS1 signaling

The progression of distant metastasis cascade is a multistep and complicated process, frequently leading to a poor prognosis in cancer patients. Recently, growing evidence has indicated that deregulation of microRNAs (miRNAs) contributes to tumorigenesis and tumor progression in colorectal cancer (C...

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Udgivet i:Oncotarget
Main Authors: Shen, Zhan-long, Wang, Bo, Jiang, Ke-wei, Ye, Chun-xiang, Cheng, Cheng, Yan, Yi-chao, Zhang, Ji-zhun, Yang, Yang, Gao, Zhi-dong, Ye, Ying-jiang, Wang, Shan
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085212/
https://ncbi.nlm.nih.gov/pubmed/27145368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9042
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