PKG II reverses HGF-triggered cellular activities by phosphorylating serine 985 of c-Met in gastric cancer cells

Previous studies showed that type II cGMP-dependent protein kinase G (PKG II) could inhibit the activation of epidermal growth factor receptor (EGFR). Both c-Met and EGFR belong to family of receptor tyrosine kinases (RTKs) and have high molecular analogy. However, the effect of PKG II on c-Met acti...

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Vydáno v:Oncotarget
Hlavní autoři: Wu, Yan, Yao, Xiaoyuan, Zhu, Miaolin, Qian, Hai, Jiang, Lu, Lan, Ting, Wu, Min, Pang, Ji, Chen, Yongchang
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085148/
https://ncbi.nlm.nih.gov/pubmed/27147579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9074
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