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Genetic identification of two major modifier loci of polycystic kidney disease progression in pcy mice.

Unlike the uniform disease progression in inbred animals, polycystic kidney disease (PKD) progression within human families can be highly variable. This may be due to environmental or genetic factors or both. To determine if PKD severity can be influenced by modifier genes, we carried out an intercr...

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Bibliographic Details
Main Authors: Woo, D D, Nguyen, D K, Khatibi, N, Olsen, P
Format: Artigo
Language:Inglês
Published: 1997
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC508382/
https://ncbi.nlm.nih.gov/pubmed/9329956
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