Prion-Seeding Activity Is widely Distributed in Tissues of Sporadic Creutzfeldt-Jakob Disease Patients

Human prion diseases are neurodegenerative disorders caused by abnormally folded prion proteins in the central nervous system. These proteins can be detected using the quaking-induced conversion assay. Compared with other bioassays, this assay is extremely sensitive and was used in the present study...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:EBioMedicine
Autori principali: Takatsuki, Hanae, Fuse, Takayuki, Nakagaki, Takehiro, Mori, Tsuyoshi, Mihara, Ban, Takao, Masaki, Iwasaki, Yasushi, Yoshida, Mari, Murayama, Shigeo, Atarashi, Ryuichiro, Nishida, Noriyuki, Satoh, Katsuya
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2016
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078574/
https://ncbi.nlm.nih.gov/pubmed/27612591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.08.033
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