Absence of Protoheme IX Farnesyltransferase CtaB Causes Virulence Attenuation but Enhances Pigment Production and Persister Survival in MRSA

The membrane protein CtaB in S. aureus is a protoheme IX farnesyltransferase involved in the synthesis of the heme containing terminal oxidases of bacterial respiratory chain. In this study, to assess the role of CtaB in S. aureus virulence, pigment production, and persister formation, we constructe...

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Bibliographic Details
Published in:Front Microbiol
Main Authors: Xu, Tao, Han, Jian, Zhang, Jia, Chen, Jiazhen, Wu, Nan, Zhang, Wenhong, Zhang, Ying
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076432/
https://ncbi.nlm.nih.gov/pubmed/27822202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2016.01625
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