‘Artilysation’ of endolysin λSa2lys strongly improves its enzymatic and antibacterial activity against streptococci

Endolysins constitute a promising class of antibacterials against Gram-positive bacteria. Recently, endolysins have been engineered with selected peptides to obtain a new generation of lytic proteins, Artilysins, with specific activity against Gram-negative bacteria. Here, we demonstrate that artily...

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Vydáno v:Sci Rep
Hlavní autoři: Rodríguez-Rubio, Lorena, Chang, Wai-Ling, Gutiérrez, Diana, Lavigne, Rob, Martínez, Beatriz, Rodríguez, Ana, Govers, Sander K., Aertsen, Abram, Hirl, Christine, Biebl, Manfred, Briers, Yves, García, Pilar
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075790/
https://ncbi.nlm.nih.gov/pubmed/27775093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35382
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