Compartmentation of Metabolites in Regulating Epigenomes of Cancer

Covalent modifications of DNA and histones are important epigenetic events and the genomewide reshaping of epigenetic markers is common in cancer. Epigenetic markers are produced by enzymatic reactions, and some of these reactions require the presence of metabolites, specifically Epigenetic Enzyme R...

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Bibliographic Details
Published in:Mol Med
Main Authors: Zhao, Zhiqiang, Wang, Li, Di, Li-jun
Format: Artigo
Language:Inglês
Published: Feinstein Institute for Medical Research 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5072407/
https://ncbi.nlm.nih.gov/pubmed/27258652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2016.00051
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