Human Cytochrome P450 Enzyme Modulation by Gymnema sylvestre: A Predictive Safety Evaluation by LC-MS/MS

BACKGROUND: Traditionally GS is used to treat diabetes mellitus. Drug-herb interaction of GS via cytochrome P450 enzyme system by substrate cocktail method using HLM has not been reported. OBJECTIVE: To evaluate the in-vitro modulatory effects of GS extracts (aqueous, methanol, ethyl acetate, chloro...

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Detalhes bibliográficos
Publicado no:Pharmacogn Mag
Main Authors: Rammohan, Bera, Samit, Karmakar, Chinmoy, Das, Arup, Saha, Amit, Kundu, Ratul, Sarkar, Sanmoy, Karmakar, Dipan, Adhikari, Tuhinadri, Sen
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068113/
https://ncbi.nlm.nih.gov/pubmed/27761064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0973-1296.191441
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