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Impact of the Choice of Normalization Method on Molecular Cancer Class Discovery Using Nonnegative Matrix Factorization

Nonnegative Matrix Factorization (NMF) has proved to be an effective method for unsupervised clustering analysis of gene expression data. By the nonnegativity constraint, NMF provides a decomposition of the data matrix into two matrices that have been used for clustering analysis. However, the decom...

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Pubblicato in:PLoS One
Autori principali: Yang, Haixuan, Seoighe, Cathal
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065197/
https://ncbi.nlm.nih.gov/pubmed/27741311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0164880
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