N-acetylcysteine attenuates myocardial dysfunction and postischemic injury by restoring caveolin-3/eNOS signaling in diabetic rats

BACKGROUND: Patients with diabetes are prone to develop cardiac hypertrophy and more susceptible to myocardial ischemia–reperfusion (I/R) injury, which are concomitant with hyperglycemia-induced oxidative stress and impaired endothelial nitric oxide (NO) synthase (eNOS)/NO signaling. Caveolae are cr...

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Detalhes bibliográficos
Publicado no:Cardiovasc Diabetol
Main Authors: Su, Wating, Zhang, Yuan, Zhang, Qiongxia, Xu, Jinjin, Zhan, Liying, Zhu, Qiqi, Lian, Qingquan, Liu, Huimin, Xia, Zhong-yuan, Xia, Zhengyuan, Lei, Shaoqing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062884/
https://ncbi.nlm.nih.gov/pubmed/27733157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-016-0460-z
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