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Designer Leptin Receptor Antagonist Allo-aca Inhibits VEGF Effects in Ophthalmic Neoangiogenesis Models
Experimental and clinical data suggest that pro-angiogenic, pro-inflammatory and mitogenic cytokine leptin can be implicated in ocular neovascularization and other eye pathologies. At least in part, leptin action appears to be mediated through functional interplay with vascular endothelial growth fa...
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Publicado en: | Front Mol Biosci |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
Frontiers Media S.A.
2016
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5062870/ https://ncbi.nlm.nih.gov/pubmed/27790618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2016.00067 |
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