Designer Leptin Receptor Antagonist Allo-aca Inhibits VEGF Effects in Ophthalmic Neoangiogenesis Models

Experimental and clinical data suggest that pro-angiogenic, pro-inflammatory and mitogenic cytokine leptin can be implicated in ocular neovascularization and other eye pathologies. At least in part, leptin action appears to be mediated through functional interplay with vascular endothelial growth fa...

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Bibliografiske detaljer
Udgivet i:Front Mol Biosci
Main Authors: Coroniti, Roberta, Farjo, Rafal, Nuno, Didier J., Otvos, Laszlo, Scolaro, Laura, Surmacz, Eva
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2016
Fag:
Molecular Biosciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062870/
https://ncbi.nlm.nih.gov/pubmed/27790618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2016.00067
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