Designer Leptin Receptor Antagonist Allo-aca Inhibits VEGF Effects in Ophthalmic Neoangiogenesis Models

Experimental and clinical data suggest that pro-angiogenic, pro-inflammatory and mitogenic cytokine leptin can be implicated in ocular neovascularization and other eye pathologies. At least in part, leptin action appears to be mediated through functional interplay with vascular endothelial growth fa...

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Vydáno v:Front Mol Biosci
Hlavní autoři: Coroniti, Roberta, Farjo, Rafal, Nuno, Didier J., Otvos, Laszlo, Scolaro, Laura, Surmacz, Eva
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2016
Témata:
Molecular Biosciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062870/
https://ncbi.nlm.nih.gov/pubmed/27790618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2016.00067
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