Designer Leptin Receptor Antagonist Allo-aca Inhibits VEGF Effects in Ophthalmic Neoangiogenesis Models

Experimental and clinical data suggest that pro-angiogenic, pro-inflammatory and mitogenic cytokine leptin can be implicated in ocular neovascularization and other eye pathologies. At least in part, leptin action appears to be mediated through functional interplay with vascular endothelial growth fa...

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Publicat a:Front Mol Biosci
Autors principals: Coroniti, Roberta, Farjo, Rafal, Nuno, Didier J., Otvos, Laszlo, Scolaro, Laura, Surmacz, Eva
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2016
Matèries:
Molecular Biosciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062870/
https://ncbi.nlm.nih.gov/pubmed/27790618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2016.00067
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