Pharmacologic inhibition of reactive gliosis blocks TNF-α-mediated neuronal apoptosis

Reactive gliosis is an early pathological feature common to most neurodegenerative diseases, yet its regulation and impact remain poorly understood. Normally astrocytes maintain a critical homeostatic balance. After stress or injury they undergo rapid parainflammatory activation, characterized by hy...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Livne-Bar, Izhar, Lam, Susy, Chan, Darren, Guo, Xiaoxin, Askar, Idil, Nahirnyj, Adrian, Flanagan, John G, Sivak, Jeremy M
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059876/
https://ncbi.nlm.nih.gov/pubmed/27685630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.277
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