Sphingosine 1-Phosphate Activation of EGFR As a Novel Target for Meningitic Escherichia coli Penetration of the Blood-Brain Barrier

Central nervous system (CNS) infection continues to be an important cause of mortality and morbidity, necessitating new approaches for investigating its pathogenesis, prevention and therapy. Escherichia coli is the most common Gram-negative bacillary organism causing meningitis, which develops follo...

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Vydáno v:PLoS Pathog
Hlavní autoři: Wang, Xiangru, Maruvada, Ravi, Morris, Andrew J., Liu, Jun O., Wolfgang, Michael J., Baek, Dong Jae, Bittman, Robert, Kim, Kwang Sik
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053521/
https://ncbi.nlm.nih.gov/pubmed/27711202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005926
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