Multi-omics analysis reveals regulators of the response to PDGF-BB treatment in pulmonary artery smooth muscle cells

BACKGROUND: Pulmonary arterial hypertension (PAH) is a lethal disease with pronounced narrowing of pulmonary vessels due to abnormal cell proliferation. The platelet-derived growth factor BB (PDGF-BB) is well known as a potent mitogen for smooth muscle cell proliferation. To better understand how th...

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Detalles Bibliográficos
Publicado en:BMC Genomics
Main Authors: Chen, Jidong, Cui, Xiaolei, Qian, Zhengjiang, Li, Yanjiao, Kang, Kang, Qu, Junle, Li, Li, Gou, Deming
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053085/
https://ncbi.nlm.nih.gov/pubmed/27716141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-3122-3
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