A C-terminal amphipathic helix is necessary for the in vivo tubule-shaping function of a plant reticulon

Reticulons (RTNs) are a class of endoplasmic reticulum (ER) membrane proteins that are capable of maintaining high membrane curvature, thus helping shape the ER membrane into tubules. The mechanism of action of RTNs is hypothesized to be a combination of wedging, resulting from the transmembrane top...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Breeze, Emily, Dzimitrowicz, Natasha, Kriechbaumer, Verena, Brooks, Rhiannon, Botchway, Stanley W., Brady, Jacob P., Hawes, Chris, Dixon, Ann M., Schnell, Jason R., Fricker, Mark D., Frigerio, Lorenzo
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2016
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047209/
https://ncbi.nlm.nih.gov/pubmed/27621477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605434113
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