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In vivo dual-delivery of glucagon like peptide-1 (GLP-1) and dipeptidyl peptidase-4 (DPP4) inhibitor through composites prepared by microfluidics for diabetes therapy

Oral delivery of proteins is still a challenge in the pharmaceutical field. Nanoparticles are among the most promising carrier systems for the oral delivery of proteins by increasing their oral bioavailability. However, most of the existent data regarding nanosystems for oral protein delivery is fro...

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發表在:Nanoscale
Main Authors: Araújo, F., Shrestha, N., Gomes, M. J., Herranz-Blanco, B., Liu, D., Hirvonen, J. J., Granja, P. L., Santos, H. A., Sarmento, B.
格式: Artigo
語言:Inglês
出版: Royal Society of Chemistry 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047059/
https://ncbi.nlm.nih.gov/pubmed/27150301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6nr00294c
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