Haploinsufficiency for NR3C1, the gene encoding the glucocorticoid receptor, in blastic plasmacytoid dendritic cell neoplasms

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and highly aggressive leukemia for which knowledge on disease mechanisms and effective therapies are currently lacking. Only a handful of recurring genetic mutations have been identified and none is specific to BPDCN. In this study, thro...

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發表在:Blood
Main Authors: Emadali, Anouk, Hoghoughi, Neda, Duley, Samuel, Hajmirza, Azadeh, Verhoeyen, Els, Cosset, Francois-Loic, Bertrand, Philippe, Roumier, Christophe, Roggy, Anne, Suchaud-Martin, Céline, Chauvet, Martine, Bertrand, Sarah, Hamaidia, Sieme, Rousseaux, Sophie, Josserand, Véronique, Charles, Julie, Templier, Isabelle, Maeda, Takahiro, Bruder-Costa, Juliana, Chaperot, Laurence, Plumas, Joel, Jacob, Marie-Christine, Bonnefoix, Thierry, Park, Sophie, Gressin, Remy, Tensen, Cornelis P., Mecucci, Cristina, Macintyre, Elizabeth, Leroux, Dominique, Brambilla, Elisabeth, Nguyen-Khac, Florence, Luquet, Isabelle, Penther, Dominique, Bastard, Christian, Jardin, Fabrice, Lefebvre, Christine, Garnache, Francine, Callanan, Mary B.
格式: Artigo
語言:Inglês
出版: American Society of Hematology 2016
主題:
Myeloid Neoplasia
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043425/
https://ncbi.nlm.nih.gov/pubmed/27060168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-09-671040
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