Novel Synthetic Oxazines Target NF-κB in Colon Cancer In Vitro and Inflammatory Bowel Disease In Vivo

Aberrant activation of nuclear factor kappa B (NF-κB) has been linked with the pathogenesis of several proinflammatory diseases including number of cancers and inflammatory bowel diseases. In the present work, we evaluated the anticancer activity of 1,2-oxazines derivatives against colorectal cancer...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Nirvanappa, Anilkumar C., Mohan, Chakrabhavi Dhananjaya, Rangappa, Shobith, Ananda, Hanumappa, Sukhorukov, Alexey Yu, Shanmugam, Muthu K., Sundaram, Mahalingam S., Nayaka, Siddaiah Chandra, Girish, Kesturu S., Chinnathambi, Arunachalam, Zayed, M. E., Alharbi, Sulaiman Ali, Sethi, Gautam, Basappa, Rangappa, Kanchugarakoppal S.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042377/
https://ncbi.nlm.nih.gov/pubmed/27685808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163209
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