Novel Synthetic Oxazines Target NF-κB in Colon Cancer In Vitro and Inflammatory Bowel Disease In Vivo

Aberrant activation of nuclear factor kappa B (NF-κB) has been linked with the pathogenesis of several proinflammatory diseases including number of cancers and inflammatory bowel diseases. In the present work, we evaluated the anticancer activity of 1,2-oxazines derivatives against colorectal cancer...

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Publicado en:PLoS One
Autores principales: Nirvanappa, Anilkumar C., Mohan, Chakrabhavi Dhananjaya, Rangappa, Shobith, Ananda, Hanumappa, Sukhorukov, Alexey Yu, Shanmugam, Muthu K., Sundaram, Mahalingam S., Nayaka, Siddaiah Chandra, Girish, Kesturu S., Chinnathambi, Arunachalam, Zayed, M. E., Alharbi, Sulaiman Ali, Sethi, Gautam, Basappa, Rangappa, Kanchugarakoppal S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042377/
https://ncbi.nlm.nih.gov/pubmed/27685808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163209
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