Novel Synthetic Oxazines Target NF-κB in Colon Cancer In Vitro and Inflammatory Bowel Disease In Vivo

Aberrant activation of nuclear factor kappa B (NF-κB) has been linked with the pathogenesis of several proinflammatory diseases including number of cancers and inflammatory bowel diseases. In the present work, we evaluated the anticancer activity of 1,2-oxazines derivatives against colorectal cancer...

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Veröffentlicht in:PLoS One
Hauptverfasser: Nirvanappa, Anilkumar C., Mohan, Chakrabhavi Dhananjaya, Rangappa, Shobith, Ananda, Hanumappa, Sukhorukov, Alexey Yu, Shanmugam, Muthu K., Sundaram, Mahalingam S., Nayaka, Siddaiah Chandra, Girish, Kesturu S., Chinnathambi, Arunachalam, Zayed, M. E., Alharbi, Sulaiman Ali, Sethi, Gautam, Basappa, Rangappa, Kanchugarakoppal S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042377/
https://ncbi.nlm.nih.gov/pubmed/27685808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163209
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