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Structural characterization of single nucleotide variants at ligand binding sites and enzyme active sites of human proteins

Functional sites on proteins play an important role in various molecular interactions and reactions between proteins and other molecules. Thus, mutations in functional sites can severely affect the overall phenotype. Progress of genome sequencing projects has yielded a wealth of information on singl...

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Detalhes bibliográficos
Publicado no:Biophys Physicobiol
Main Authors: Yamada, Kazunori D., Nishi, Hafumi, Nakata, Junichi, Kinoshita, Kengo
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society of Japan (BSJ) 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042176/
https://ncbi.nlm.nih.gov/pubmed/27924270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2142/biophysico.13.0_157
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