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APE1 polymorphic variants cause persistent genomic stress and affect cancer cell proliferation
Apurinic/apyrimidinic endonuclease 1 (APE1) is the main mammalian AP-endonuclease responsible for the repair of endogenous DNA damage through the base excision repair (BER) pathway. Molecular epidemiological studies have identified several genetic variants associated with human diseases, but a well-...
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| Publicat a: | Oncotarget |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Impact Journals LLC
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5041981/ https://ncbi.nlm.nih.gov/pubmed/27050370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8477 |
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