Efficacy Projection of Obiltoxaximab for Treatment of Inhalational Anthrax across a Range of Disease Severity

Inhalational anthrax has high mortality even with antibiotic treatment, and antitoxins are now recommended as an adjunct to standard antimicrobial regimens. The efficacy of obiltoxaximab, a monoclonal antibody against anthrax protective antigen (PA), was examined in multiple studies conducted in two...

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Bibliografski detalji
Izdano u:Antimicrob Agents Chemother
Glavni autori: Yamamoto, Brent J., Shadiack, Annette M., Carpenter, Sarah, Sanford, Daniel, Henning, Lisa N., O'Connor, Edward, Gonzales, Nestor, Mondick, John, French, Jonathan, Stark, Gregory V., Fisher, Alan C., Casey, Leslie S., Serbina, Natalya V.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2016
Teme:
Clinical Therapeutics
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038317/
https://ncbi.nlm.nih.gov/pubmed/27431222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00972-16
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