Efficacy Projection of Obiltoxaximab for Treatment of Inhalational Anthrax across a Range of Disease Severity

Inhalational anthrax has high mortality even with antibiotic treatment, and antitoxins are now recommended as an adjunct to standard antimicrobial regimens. The efficacy of obiltoxaximab, a monoclonal antibody against anthrax protective antigen (PA), was examined in multiple studies conducted in two...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Yamamoto, Brent J., Shadiack, Annette M., Carpenter, Sarah, Sanford, Daniel, Henning, Lisa N., O'Connor, Edward, Gonzales, Nestor, Mondick, John, French, Jonathan, Stark, Gregory V., Fisher, Alan C., Casey, Leslie S., Serbina, Natalya V.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Clinical Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038317/
https://ncbi.nlm.nih.gov/pubmed/27431222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00972-16
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