Changes in peripheral blood lymphocytes in polycythemia vera and essential thrombocythemia patients treated with pegylated-interferon alpha and correlation with JAK2(V617F) allelic burden

BACKGROUND: Pegylated-interferon alpha (PegINFα) treatment of patients with polycythemia vera (PV) and essential thrombocythemia (ET) has resulted in long-term clinical response, decreased JAK2 (V617F) allelic burden and restoration of polyclonal hematopoiesis. The mechanisms of the beneficial effec...

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Bibliographic Details
Published in:Exp Hematol Oncol
Main Authors: Kovacsovics-Bankowski, Magdalena, Kelley, Todd W., Efimova, Olga, Kim, Soo Jin, Wilson, Andrew, Swierczek, Sabina, Prchal, Josef
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037882/
https://ncbi.nlm.nih.gov/pubmed/27708986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-016-0057-y
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