Telomere dysfunction in alveolar epithelial cells causes lung remodeling and fibrosis

Telomeres are short in type II alveolar epithelial cells (AECs) of patients with idiopathic pulmonary fibrosis (IPF). Whether dysfunctional telomeres contribute directly to development of lung fibrosis remains unknown. The objective of this study was to investigate whether telomere dysfunction in ty...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Naikawadi, Ram P., Disayabutr, Supparerk, Mallavia, Benat, Donne, Matthew L., Green, Gary, La, Janet L., Rock, Jason R., Looney, Mark R., Wolters, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033906/
https://ncbi.nlm.nih.gov/pubmed/27699234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.86704
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