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PRL3-zumab, a first-in-class humanized antibody for cancer therapy
Novel, tumor-specific drugs are urgently needed for a breakthrough in cancer therapy. Herein, we generated a first-in-class humanized antibody (PRL3-zumab) against PRL-3, an intracellular tumor-associated phosphatase upregulated in multiple human cancers, for unconventional cancer immunotherapies. W...
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| Publicat a: | JCI Insight |
|---|---|
| Autors principals: | , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5033845/ https://ncbi.nlm.nih.gov/pubmed/27699276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.87607 |
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