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Chemotherapy induces expression and release of heparanase leading to changes associated with an aggressive tumor phenotype
High heparanase expression is associated with enhanced tumor growth, angiogenesis, and metastasis in many types of cancer. However, the mechanisms driving high heparanase expression are not fully understood. In the present study, we discovered that drugs used in the treatment of myeloma upregulate h...
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| Publicado no: | Matrix Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5033659/ https://ncbi.nlm.nih.gov/pubmed/27016342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2016.03.006 |
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