Circulating Calreticulin Is Increased in Myelofibrosis: Correlation with Interleukin-6 Plasma Levels, Bone Marrow Fibrosis, and Splenomegaly

Myelofibrosis (MF) is a clonal neoplasia of the hemopoietic stem/progenitor cells associated with genetic mutations in the Janus kinase 2 (JAK2), myeloproliferative leukemia virus oncogene (MPL), and calreticulin (CALR) genes. MF is also characterized by a state of chronic inflammation. Calreticulin...

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Publicat a:Mediators Inflamm
Autors principals: Sollazzo, Daria, Forte, Dorian, Polverelli, Nicola, Perricone, Margherita, Romano, Marco, Luatti, Simona, Vianelli, Nicola, Cavo, Michele, Palandri, Francesca, Catani, Lucia
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031875/
https://ncbi.nlm.nih.gov/pubmed/27672242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/5860657
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