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Local microRNA delivery targets Palladin and prevents metastatic breast cancer

Metastasis is the primary cause for mortality in breast cancer. MicroRNAs, gene expression master regulators, constitute an attractive candidate to control metastasis. Here we show that breast cancer metastasis can be prevented by miR-96 or miR-182 treatment, and decipher the mechanism of action. We...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Gilam, Avital, Conde, João, Weissglas-Volkov, Daphna, Oliva, Nuria, Friedman, Eitan, Artzi, Natalie, Shomron, Noam
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031803/
https://ncbi.nlm.nih.gov/pubmed/27641360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12868
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