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EZH2 enhances the differentiation of fibroblasts into myofibroblasts in idiopathic pulmonary fibrosis

The accumulation of fibroblasts/myofibroblasts in fibrotic foci is one of the characteristics of idiopathic pulmonary fibrosis (IPF). Enhancer of zeste homolog 2 (EZH2) is the catalytic component of a multiprotein complex, polycomb repressive complex 2, which is involved in the trimethylation of his...

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Foilsithe in:Physiol Rep
Main Authors: Xiao, Xiao, Senavirathna, Lakmini K., Gou, Xuxu, Huang, Chaoqun, Liang, Yurong, Liu, Lin
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027349/
https://ncbi.nlm.nih.gov/pubmed/27582065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12915
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