Time-kill curve analysis and pharmacodynamic modelling for in vitro evaluation of antimicrobials against Neisseria gonorrhoeae

BACKGROUND: Gonorrhoea is a sexually transmitted infection caused by the Gram-negative bacterium Neisseria gonorrhoeae. Resistance to first-line empirical monotherapy has emerged, so robust methods are needed to evaluate the activity of existing and novel antimicrobials against the bacterium. Pharma...

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Udgivet i:BMC Microbiol
Main Authors: Foerster, Sunniva, Unemo, Magnus, Hathaway, Lucy J., Low, Nicola, Althaus, Christian L.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Methodology Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027106/
https://ncbi.nlm.nih.gov/pubmed/27639378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-016-0838-9
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