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Insulin-Like Growth Factor-1 but Not Insulin Predicts Cognitive Decline in Huntington’s Disease

BACKGROUND: Huntington's disease (HD) is one of several neurodegenerative disorders that have been associated with metabolic alterations. Changes in Insulin Growth Factor 1 (IGF-1) and/or insulin input to the brain may underlie or contribute to the progress of neurodegenerative processes. Here,...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Salem, Linda, Saleh, Nadine, Désaméricq, Gaelle, Youssov, Katia, Dolbeau, Guillaume, Cleret, Laurent, Bourhis, Marie-Laure, Azulay, Jean-Philippe, Krystkowiak, Pierre, Verny, Christophe, Morin, Françoise, Moutereau, Stéphane, Bachoud-Lévi, Anne-Catherine, Maison, Patrick
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023180/
https://ncbi.nlm.nih.gov/pubmed/27627435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162890
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