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Translocation of Endogenous Danger Signal HMGB1 From Nucleus to Membrane Microvesicles in Macrophages

High mobility group box 1 (HMGB1) is a nuclear protein that can be released from activated or dead cells. Extracellular HMGB1 can serve as a “danger signal” and novel cytokine that mediates sterile inflammation. In addition to its soluble form, extracellular HMGB1 can also be carried by membrane mic...

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Vydáno v:J Cell Physiol
Hlavní autoři: CHEN, YAN, LI, GUANGPING, LIU, YANXIA, WERTH, VICTORIA P., WILLIAMS, KEVIN JON, LIU, MING-LIN
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021294/
https://ncbi.nlm.nih.gov/pubmed/26909509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25352
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