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3-D individual cell based computational modeling of tumor cell–macrophage paracrine signaling mediated by EGF and CSF-1 gradients()

High density of macrophages in mammary tumors has been associated with a higher risk of metastasis and thus increased mortality in women. The EGF/CSF-1 paracrine signaling increases the number of invasive tumor cells by both recruiting tumor cells further away and manipulating the macrophages’ innat...

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Foilsithe in:Integr Biol (Camb)
Main Authors: Knutsdottir, Hildur, Condeelis, John S., Palsson, Eirikur
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013833/
https://ncbi.nlm.nih.gov/pubmed/26686751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5ib00201j
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