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RNA remodeling activity of DEAD-box proteins tuned by protein concentration, RNA length and ATP

DEAD-box RNA helicases play central roles in RNP biogenesis. We reported earlier that LAF-1, a DEAD-box RNA helicase in C. elegans, dynamically interacts with RNA and that the interaction likely contributes to the fluidity of RNP droplets. Here, we investigate the molecular basis of the interaction...

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Bibliografske podrobnosti
izdano v:Mol Cell
Main Authors: Kim, Younghoon, Myong, Sua
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010468/
https://ncbi.nlm.nih.gov/pubmed/27546789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.07.010
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