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RNA remodeling activity of DEAD-box proteins tuned by protein concentration, RNA length and ATP

DEAD-box RNA helicases play central roles in RNP biogenesis. We reported earlier that LAF-1, a DEAD-box RNA helicase in C. elegans, dynamically interacts with RNA and that the interaction likely contributes to the fluidity of RNP droplets. Here, we investigate the molecular basis of the interaction...

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Detalles Bibliográficos
Publicado en:Mol Cell
Main Authors: Kim, Younghoon, Myong, Sua
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010468/
https://ncbi.nlm.nih.gov/pubmed/27546789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.07.010
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