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RNA remodeling activity of DEAD-box proteins tuned by protein concentration, RNA length and ATP

DEAD-box RNA helicases play central roles in RNP biogenesis. We reported earlier that LAF-1, a DEAD-box RNA helicase in C. elegans, dynamically interacts with RNA and that the interaction likely contributes to the fluidity of RNP droplets. Here, we investigate the molecular basis of the interaction...

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Détails bibliographiques
Publié dans:Mol Cell
Auteurs principaux: Kim, Younghoon, Myong, Sua
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010468/
https://ncbi.nlm.nih.gov/pubmed/27546789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.07.010
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