Plerixafor (a CXCR4 antagonist) following myeloablative allogeneic hematopoietic stem cell transplantation enhances hematopoietic recovery

BACKGROUND: The binding of CXCR4 with its ligand (stromal-derived factor-1) maintains hematopoietic stem/progenitor cells (HSPCs) in a quiescent state. We hypothesized that blocking CXCR4/SDF-1 interaction after hematopoietic stem cell transplantation (HSCT) promotes hematopoiesis by inducing HSC pr...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Hematol Oncol
मुख्य लेखकों: Green, Michael M. B., Chao, Nelson, Chhabra, Saurabh, Corbet, Kelly, Gasparetto, Cristina, Horwitz, Ari, Li, Zhiguo, Venkata, Jagadish Kummetha, Long, Gwynn, Mims, Alice, Rizzieri, David, Sarantopoulos, Stefanie, Stuart, Robert, Sung, Anthony D., Sullivan, Keith M., Costa, Luciano, Horwitz, Mitchell, Kang, Yubin
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2016
विषय:
Research
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4989381/
https://ncbi.nlm.nih.gov/pubmed/27535663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0301-2
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