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Phloroglucinol protects retinal pigment epithelium and photoreceptor against all‐trans‐retinal–induced toxicity and inhibits A2E formation

Among retinal macular diseases, the juvenile recessive Stargardt disease and the age‐related degenerative disease arise from carbonyl and oxidative stresses (COS). Both stresses originate from an accumulation of all‐trans‐retinal (at RAL) and are involved in bisretinoid formation by condensation of...

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Библиографические подробности
Опубликовано в: :J Cell Mol Med
Главные авторы: Cia, David, Cubizolle, Aurélie, Crauste, Céline, Jacquemot, Nathalie, Guillou, Laurent, Vigor, Claire, Angebault, Claire, Hamel, Christian P., Vercauteren, Joseph, Brabet, Philippe
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988284/
https://ncbi.nlm.nih.gov/pubmed/27072643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12857
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