Phloroglucinol protects retinal pigment epithelium and photoreceptor against all‐trans‐retinal–induced toxicity and inhibits A2E formation

Among retinal macular diseases, the juvenile recessive Stargardt disease and the age‐related degenerative disease arise from carbonyl and oxidative stresses (COS). Both stresses originate from an accumulation of all‐trans‐retinal (at RAL) and are involved in bisretinoid formation by condensation of...

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Dettagli Bibliografici
Pubblicato in:J Cell Mol Med
Autori principali: Cia, David, Cubizolle, Aurélie, Crauste, Céline, Jacquemot, Nathalie, Guillou, Laurent, Vigor, Claire, Angebault, Claire, Hamel, Christian P., Vercauteren, Joseph, Brabet, Philippe
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988284/
https://ncbi.nlm.nih.gov/pubmed/27072643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12857
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