Phloroglucinol protects retinal pigment epithelium and photoreceptor against all‐trans‐retinal–induced toxicity and inhibits A2E formation

Among retinal macular diseases, the juvenile recessive Stargardt disease and the age‐related degenerative disease arise from carbonyl and oxidative stresses (COS). Both stresses originate from an accumulation of all‐trans‐retinal (at RAL) and are involved in bisretinoid formation by condensation of...

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Dades bibliogràfiques
Publicat a:J Cell Mol Med
Autors principals: Cia, David, Cubizolle, Aurélie, Crauste, Céline, Jacquemot, Nathalie, Guillou, Laurent, Vigor, Claire, Angebault, Claire, Hamel, Christian P., Vercauteren, Joseph, Brabet, Philippe
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988284/
https://ncbi.nlm.nih.gov/pubmed/27072643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12857
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