Superior therapeutic efficacy of nab-paclitaxel over cremophor-based paclitaxel in locally advanced and metastatic models of human pancreatic cancer

BACKGROUND: Albumin-bound paclitaxel (nab-paclitaxel, nab-PTX) plus gemcitabine (GEM) combination has demonstrated efficient antitumour activity and statistically significant overall survival of patients with metastatic pancreatic ductal adenocarcinoma (PDAC) compared with GEM monotherapy. This regi...

Full description

Saved in:
Bibliographic Details
Published in:Br J Cancer
Main Authors: Rajeshkumar, N V, Yabuuchi, Shinichi, Pai, Shweta G, Tong, Zeen, Hou, Shihe, Bateman, Scott, Pierce, Daniel W, Heise, Carla, Von Hoff, Daniel D, Maitra, Anirban, Hidalgo, Manuel
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
Subjects:
Translational Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985357/
https://ncbi.nlm.nih.gov/pubmed/27441498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.215
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items