The abundance of cis-acting loci leading to differential allele expression in F1 mice and their relationship to loci harboring genes affecting complex traits

BACKGROUND: Genome-wide surveys have detected cis-acting quantitative trait loci altering levels of RNA transcripts (RNA-eQTLs) by associating SNV alleles to transcript levels. However, the sensitivity and specificity of detection of cis- expression quantitative trait loci (eQTLs) by genetic approac...

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Veröffentlicht in:BMC Genomics
Hauptverfasser: Yeo, Seungeun, Hodgkinson, Colin A., Zhou, Zhifeng, Jung, Jeesun, Leung, Ming, Yuan, Qiaoping, Goldman, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982227/
https://ncbi.nlm.nih.gov/pubmed/27515598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2922-9
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